Azvudine New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP34041CAS No. ：1011529-10-4Purity：98%

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CAS No.	1011529-10-4	Cat. No.	BCP34041
Name	Azvudine
Synonyms	RO-0622;RO 0622;RO0622;
SMILES	C1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)F
Chemical Name
Formula	C9H11FN6O4	M. Wt	286.22
Purity	98%	Storage	Store at 4-8°C
Description	Azvudine is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine exerts highly potent inhibition on HIV-1 (EC50s ranging from 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM). Azvudine inhibits NRTI-resistant viral strains[1]. Azvudine is a click chemistry reagent, itcontains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.