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MK-8245 Chemical Structure

MK-8245

Data Sheet For research use only. Not for human use.
Cat. No. :BCP06568CAS No. :1030612-87-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1030612-87-3 Cat. No. BCP06568
Name MK-8245
Synonyms MK 8245;MK8245;
SMILES
Chemical Name
Formula C16H15BrFN7O3S M. Wt 484.3
Purity 98% Storage Store at 4-8°C
Description MK-8245 is a potent, liver-targeted SCD inhibitor with preclinical antidiabetic and antidyslipidemic efficacy with a significantly improved therapeutic window. MK-8245 was believed to inhibit the SCD enzyme solely in the liver and not in other tissues for the following reasons. When SCD inhibition has been measured by desaturation index in tissues of rodents treated with MK-8245, the desaturation index was significantly reduced in liver but not in other tissues such as skin, eye and adipose tissue.
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