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CAS No. | 921605-87-0 | Cat. No. | BCP46714 |
Name | MF438 | ||
Synonyms | MF-438; MF 438; | ||
SMILES | CC1=NN=C(S1)C2=NN=C(C=C2)N3CCC(CC3)OC4=CC=CC=C4C(F)(F)F | ||
Chemical Name | |||
Formula | C19H18F3N5OS | M. Wt | 421.44 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MF-438 is a potent and orally bioavailable SCD inhibitor. MF-438 exhibits good pharmacokinetics and metabolic stability, thereby serving as a valuable tool for further understanding the role of SCD inhibition in biological and pharmacological models of diseases related to metabolic disorders. Co-treatment with cisplatin and MF-438 reverts upregulation of CSCs markers, strongly synergizes in the inhibition of 3D spheroids formation and induces CSCs apoptosis. |
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