Ramelteon New
Data Sheet
For research use only. Not for human use.
Get Quotation Now Tel: 0086-17754423994 or orders@biochempartner.com
Real-Time Inquiry ×
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 196597-26-9 | Cat. No. | BCP04205 |
| Name | Ramelteon | ||
| Synonyms | TAK-375;Rozerem;TAK375;TAK 375; | ||
| SMILES | CCC(=O)NCCC1CCC2=C1C3=C(C=C2)OCC3 | ||
| Chemical Name | |||
| Formula | C16H21NO2 | M. Wt | 259.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Ramelteon inhibits forskolin-stimulated cAMP production with IC50 of 21.2 pM in CHO cells. Ramelteon has high affinity with recombinant human MT1 and MT2 receptors with pKi of 10.05 and 9.70, respectively. Ramelteon inhibits Xenopus laevis melanophore pigment granule aggregation with pEC50 of 11.48. Ramelteon (1 nM) increases ERK1/2 phosphorylation not only in MT1/MT2 cerebellar granule cells but also in cerebellar granule cells expressing only one of the two melatonin receptors. 4P-PDOT blocks the stimulatory action of Ramelteon (1 nM) in MT1 KO cerebellar granule cells, while luzindole attenuates the action of Ramelteon (1 nM) in MT2 KO cerebellar granule cells. Ramelteon (100 μM) induces any pigment dispersion while melatonin completely disperses aggregated melanophores at 10 μM. | ||
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.
Recommend Products
More >
Tags:Ramelteon supplier,Ramelteon purchase,Ramelteon manufacturer,Ramelteon distributor,Ramelteon cost,Ramelteon buy,Ramelteon for sale