Anastrozole New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 120511-73-1 | Cat. No. | BCP02090 |
| Name | Anastrozole | ||
| Synonyms | ZD-1033; ZD 1033; ZD1033; CCRIS 9352; HSDB 7462; ICI D1033; Arimidex; | ||
| SMILES | CC(C1=CC(CN2N=CN=C2)=CC(C(C)(C)C#N)=C1)(C)C#N | ||
| Chemical Name | |||
| Formula | C17H19N5 | M. Wt | 293.37 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Anastrozole has high intrinsic potency in vitro and inhibits human placental aromatase with an IC50 of 15 nM. Anastrozole it is 200 times as potent as AG, twice as potent as 4-OHA and one third as potent as fadrozole. [1]. Anastrozole inhibits aromatase by binding competitively to the hem group of the CYP unit of the enzyme thereby reducing estrogen biosynthesis in the periphery and the breast. Anastrozole has little or no effect on other steroid hormones. | ||
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