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CAS No. | 1236188-16-1 | Cat. No. | BCP16353 |
Name | 740Y-P | ||
Synonyms | 740 Y-P;740YP;740 YP;740YPDGFR; PDGFR 740Y-P;H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Ser-Asp-Gly-Gly-Tyr(PO3H2)-Met-Asp-Met-Ser-OH;RQIKIWFQNRRMKWKKSDGGXMDMS; | ||
SMILES | O=C(N[C@](C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@](C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(NCC(NCC | ||
Chemical Name | |||
Formula | C141H222N43O39PS3 | M. Wt | 3270.72 |
Purity | 98% | Storage | Store at 4-8°C |
Description | 740 Y-P is a cell-permeable phosphopeptide activator of PI3K. It binds to the p85 N- and C-terminal SH2 domains of PI3K but not to GST or the N-terminal domain of phospholipase C (PLC) in an affinity purification assay. And it displays mitogenic activity in C2 muscle cells and promotes survival of rat cerebellar granule neurons in vitro. |
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