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CAS No. | 130717-51-0 | Cat. No. | BCP35730 |
Name | FR 122047 hydrochloride | ||
Synonyms | FR-122047 HCl; FR 122047 HCl; FR122047 HCl; | ||
SMILES | CN1CCN(CC1)C(=O)C2=NC(=C(S2)C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC.Cl | ||
Chemical Name | |||
Formula | C23H26ClN3O3S | M. Wt | 459.99 |
Purity | 98% | Storage | Store at 4-8°C |
Description | FR-122047 is a potent and selective cyclooxygenase-1 (COX-1) inhibitor (IC50 values are 0.028 and 65 μM for COX-1 and COX-2 respectively). FR122047 treatment led to a distinct suppression of cell growth in MCF-7 cells. FR122047 may have an anti-cancer potential in breast cancer. |
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