(2S)-2-hydroxypentanedioic acid New
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CAS No. | 13095-48-2 | Cat. No. | BCP47205 |
Name | (2S)-2-hydroxypentanedioic acid | ||
Synonyms | L-2-hydroxyglutarate; | ||
SMILES | C(CC(=O)O)C(C(=O)O)O | ||
Chemical Name | |||
Formula | C5H8O5 | M. Wt | 148.11 |
Purity | 98% | Storage | Store at 4-8°C |
Description | (2S)-2-hydroxypentanedioic acid is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively. |
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