CZC-25146.HCl
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CAS No. | 1330003-04-7 | Cat. No. | BCP09557 |
Name | CZC-25146.HCl | ||
Synonyms | CZC-25146 hydrochloride ;CZC-25146;CZC 25146;CZC25146; | ||
SMILES | |||
Chemical Name | |||
Formula | C22H25FN6O4S.HCl | M. Wt | 525 |
Purity | 98% | Storage | Store at 4-8°C |
Description | CZC-25146 displayed a very clean profile, it inhibited only five kinases(PLK4, GAK, TNK1, CAMKK2 and PIP4K2C) with high potency, none of which have been classified as predictors of genotoxicity or hematopoietic toxicity. CZC-25146 neither caused cytotoxicity in human cortical neurons at concentrations below 5 μM over a seven-day treatment in culture nor did it block neuronal development in vitro. |
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