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CAS No. | 1351761-44-8 | Cat. No. | BCP09873 |
Related Products | 2070015-00-6(GNE7915 tosylate) | ||
Name | GNE7915 | ||
Synonyms | GNE-7915;GNE7915; | ||
SMILES | CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC | ||
Chemical Name | |||
Formula | C19H21F4N5O3 | M. Wt | 443.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | GNE-7915 is a potent LRRK2 kinase inhibitor, which possess an ideal balance of LRRK2 cellular potency, broad kinase selectivity, metabolic stability, and brain penetration across multiple species. GNE-7915 was reported as a potent (IC50=9 nM) selective (1/187 kinases), brain-penetrant and non-toxic inhibitor of LRRK2. |
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