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CAS No. | 1338542-14-5 | Cat. No. | BCP48392 |
Name | OTS964 | ||
Synonyms | OTS-964;OTS 964; | ||
SMILES | CC1=CC(=C(C2=C1NC(=O)C3=C2C=CS3)C4=CC=C(C=C4)C(C)CN(C)C)O | ||
Chemical Name | |||
Formula | C23H24N2O2S | M. Wt | 392.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | OTS964 is an orally active, high affinity and selective TOPK inhibitor with an IC50 of 28 nM. OTS964 is also a potent inhibitor of the cyclin-dependent kinase CDK11, which binds to CDK11B with a Kd of 40 nM. |
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