OTS514 hydrochloride New
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CAS No. | 2319647-76-0 | Cat. No. | BCP34816 |
Name | OTS514 hydrochloride | ||
Synonyms | OTS 514 hydrochloride;OTS514 HCl;OTS-514 HCl; | ||
SMILES | O=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2C)C4=C1SC=C4.[H]Cl | ||
Chemical Name | |||
Formula | C21H20N2O2S.HCl | M. Wt | 400.92 |
Purity | 98% | Storage | Store at 4-8°C |
Description | OTS514 hydrochloride is a highly potent TOPK inhibitor, which inhibits TOPK kinase activity with a median inhibitory concentration (IC50) value of 2.6 nM. OTS514 hydrochloride strongly suppresses the growth of TOPK-positive cancer cells. OTS514 hydrochloride induces cell cycle arrest and apoptosis. |
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