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OTS514 hydrochloride Chemical Structure

OTS514 hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP34816CAS No. :2319647-76-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2319647-76-0 Cat. No. BCP34816
Name OTS514 hydrochloride
Synonyms OTS 514 hydrochloride;OTS514 HCl;OTS-514 HCl;
SMILES O=C1NC2=C(C(C3=CC=C([C@@H](C)CN)C=C3)=C(O)C=C2C)C4=C1SC=C4.[H]Cl
Chemical Name
Formula C21H20N2O2S.HCl M. Wt 400.92
Purity 98% Storage Store at 4-8°C
Description OTS514 hydrochloride is a highly potent TOPK inhibitor, which inhibits TOPK kinase activity with a median inhibitory concentration (IC50) value of 2.6 nM. OTS514 hydrochloride strongly suppresses the growth of TOPK-positive cancer cells. OTS514 hydrochloride induces cell cycle arrest and apoptosis.
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