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CAS No. | 1359164-11-6 | Cat. No. | BCP40332 |
Name | SR 2211 | ||
Synonyms | SR2211;SR 2211; | ||
SMILES | C1CN(CCN1CC2=CC=C(C=C2)C3=C(C=C(C=C3)C(C(F)(F)F)(C(F)(F)F)O)F)CC4=CC=NC=C4 | ||
Chemical Name | |||
Formula | C26H24F7N3O | M. Wt | 527.48 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SR 2211 is a selective inverse agonist of retinoic acid receptor-related orphan receptor γ (RORγ) (Ki = 105 nM; IC50 ~320 nM). SR 2211 exhibits weak activity at liver X receptor α (LXRα) and has no effect on transcriptional activity of farnesoid X receptors (FXR) or transcriptional activity of RORα. |
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