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RI-2 Chemical Structure

RI-2

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP15320CAS No. ：1417162-36-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1417162-36-7 Cat. No. BCP15320
Name RI-2
Synonyms RI 2;RI2;
SMILES
Chemical Name
Formula C21H18Cl2N2O4 M. Wt 433.28
Purity 98% Storage Store at 4-8°C
Description RI-2 is a reversible inhibitor of RAD51 (IC50 = 44.2 μM), a protein that is central to the homologous recombination process initiated upon DNA double-strand breaks and is often overexpressed in a wide range of human cancer cell types.At 150 μM, it has been shown to inhibit DNA repair and to sensitize cancer cells to cross-linking chemotherapy in vitro.
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