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NMS-873 Chemical Structure

NMS-873

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08666CAS No. :1418013-75-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1418013-75-8 Cat. No. BCP08666
Name NMS-873
Synonyms NMS873;NMS 873;
SMILES
Chemical Name
Formula C27H28N4O3S2 M. Wt 520.67
Purity 98% Storage Store at 4-8°C
Description NMS-873 is a potent, allosteric and specific VCP inhibitor (also known as p97 inhibitor) with IC50 of 30 nM. NMS-873 activated the unfolded protein response, interfered with autophagy and induced cancer cell death. The consistent pattern of cancer cell killing by covalent and allosteric inhibitors provided critical validation of VCP as a cancer target.
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