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NVP-TNKS656 Chemical Structure

NVP-TNKS656

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28685CAS No. :1419949-20-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1419949-20-4 Cat. No. BCP28685
Name NVP-TNKS656
Synonyms NVPTNKS656; NVP TNKS656;TNKS656; TNKS-656; TNKS 656;
SMILES COC1=CC=C(C=C1)C(=O)C2CCN(CC2)CC(=O)N(CC3CC3)CC4=NC5=C(COCC5)C(=O)N4
Chemical Name
Formula C27H34N4O5 M. Wt 494.58
Purity 98% Storage Store at 4-8°C
Description NVP-TNKS656, also known as TNKS656, is a potent and orally active Tankyrase Inhibitor. With an enthalpy-driven thermodynamic signature of binding, highly favorable physicochemical properties, and high lipophilic efficiency, NVP-TNKS656 is well suited for further in vivo validation studies. Bioactivity of TNKS656: TNKS2 IC50 = 6nM, LiPE = 7.0, HEK298 STF IC50 = 3.5nM, Cmax/ Cellular IC50 = 23,000
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