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Venadaparib Chemical Structure

Venadaparib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP42946CAS No. :1681017-83-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1681017-83-3 Cat. No. BCP42946
Name Venadaparib
Synonyms IDX-1197;IDX 1197;IDX1197;
SMILES C1CC1NCC2CN(C2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F
Chemical Name
Formula C23H23FN4O2 M. Wt 406.46
Purity 98% Storage Store at 4-8°C
Description Venadaparib is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research.
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