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CAS No. | 1681017-83-3 | Cat. No. | BCP42946 |
Name | Venadaparib | ||
Synonyms | IDX-1197;IDX 1197;IDX1197; | ||
SMILES | C1CC1NCC2CN(C2)C(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F | ||
Chemical Name | |||
Formula | C23H23FN4O2 | M. Wt | 406.46 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Venadaparib is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research. |
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