RBN-2397 New
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CAS No. | 2381037-82-5 | Cat. No. | BCP33764 |
Name | RBN-2397 | ||
Synonyms | RBN2397;RBN 2397; | ||
SMILES | O=C1C(C(F)(F)F)=C(N[C@@H](C)COCCC(N2CCN(C3=NC=C(C(F)(F)F)C=N3)CC2)=O)C=NN1 | ||
Chemical Name | |||
Formula | C20H23F6N7O3 | M. Wt | 523.43 |
Purity | 98% | Storage | Store at 4-8°C |
Description | RBN-2397 is a potent, accross species and orally active NAD+ competitive inhibitor of PARP7 (IC50<3 nM). RBN-2397 selectively binds to PARP7 (Kd=0.001 μM) and restores interferon (Type I) signaling. RBN-2397 has the potential for the study of advanced or metastatic solid tumors. |
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