DDR1-IN-2 New
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| CAS No. | 1429617-90-2 | Cat. No. | BCP43189 |
| Name | DDR1-IN-2 | ||
| Synonyms | DDR1-IN-7rh; 7RH; DDR1 Inhibitor 7rh; | ||
| SMILES | CCC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)CN3CCN(CC3)C)C#CC4=CN5C(=CC=N5)N=C4 | ||
| Chemical Name | |||
| Formula | C30H29F3N6O | M. Wt | 546.59 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | DDR1-IN-2 is a potent and selective DDR1 inhibitor (IC50 = 6.8 nM). Exhibits selectivity for DDR1 over DDR2, Bcr-Abl and c-Kit (IC50 values are 101.4 and 355 nM and > 10 μM, respectively) and a range of other kinases. Inhibits proliferation of cancer cell lines expressing high levels of DDR1 in vitro and suppresses cancer cell invasion, adhesion and tumorigenicity. Orally bioavailable. | ||
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