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UCB-9260 Chemical Structure

UCB-9260

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP40717CAS No. ：1515888-53-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1515888-53-5 Cat. No. BCP40717
Name UCB-9260
Synonyms UCB 9260;UCB9260;
SMILES CC1=CC(=C(C=C1)C)CN2C3=C(C=CC(=C3)C4=CN(N=C4)C)N=C2C(C5=CC=NC=C5)O
Chemical Name
Formula C26H25N5O M. Wt 423.52
Purity 98% Storage Store at 4-8°C
Description UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13  nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation.
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