AX-024 hydrochloride New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1704801-24-0 | Cat. No. | BCP30050 |
| Name | AX-024 hydrochloride | ||
| Synonyms | AX-024 HCl;AX 024 HCl;AX024 HCl;AX024 hydrochloride ;AX 024 hydrochloride; | ||
| SMILES | COC1=CC2=C(C=C1)OCC(=C2C3=CC=C(C=C3)F)CN4CCCC4.Cl | ||
| Chemical Name | |||
| Formula | C21H23ClFNO2 | M. Wt | 375.86 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.AX-024 is an orally available inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation (IC50 value 1 nM). Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases. | ||
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