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CAS No. | 163252-36-6 | Cat. No. | BCP21097 |
Name | Clevudine | ||
Synonyms | L-FMAU; L FMAU; LFMAU; | ||
SMILES | CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F | ||
Chemical Name | |||
Formula | C10H13FN2O5 | M. Wt | 260.22 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Clevudine, also known as L-FMAU, is an antiviral used in the treatment of Hepatitis B. Clevudine is differentiated from other oral agents by an unusual activation pathway to the biochemically active triphosphate, a mechanism of action of clevudine triphosphate that inhibits multiple steps of the hepatitis B virus (HBV) intracellular life cycle, a long half-life, and significant reduction of covalently closed circular DNA (cccDNA) in animal models. |
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