Inarigivir
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CAS No. | 475650-36-3 | Cat. No. | BCP29769 |
Name | Inarigivir | ||
Synonyms | ORI-9020; ORI 9020; ORI9020; SB-40; SB-9000; SB9000;SB 9000; | ||
SMILES | COC1C(C(OC1N2C=CC(=O)NC2=O)CO)OP(=S)(O)OCC3C(CC(O3)N4C=NC5=C4N=CN=C5N)O | ||
Chemical Name | |||
Formula | C20H26N7O10PS | M. Wt | 587.50 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Inarigivir, also known as ORI-9020 and SB-9000, is a novel dinucleotide, evaluated in transgenic mice expressing hepatitis B virus (HBV), significantly reduced liver HBV DNA (P = 0.001). Levels of HBeAg and HBsAg in serum and of HBcAg in liver were not affected by treatment. A minimal effective dosage was determined to be between 1.6 and 0.5 mg/kg of body weight/day, which was similar to that observed for adefovir dipivoxil. |
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