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Avasimibe Chemical Structure

Avasimibe

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02302CAS No. :166518-60-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 166518-60-1 Cat. No. BCP02302
Name Avasimibe
Synonyms CI-1011;CI1011;CI 1011;PD-148515;PD148515;PD 148515;
SMILES CC(C)C1=C(C(=CC=C1)C(C)C)OS(=O)(=O)NC(=O)CC2=C(C=C(C=C2C(C)C)C(C)C)C(C)C
Chemical Name
Formula C29H43NO4S M. Wt 501.72
Purity 98% Storage Store at 4-8°C
Description Avasimibe is an ACAT inhibitor (IC50 = 3.3 μM). Inhibits cholesterol esterification and reduces plasma cholesterol levels in rats. Also inhibits tumor growth and prolongs survival time in a melanoma mouse model and reduces tumor growth and metastasis in a pancreatic cancer mouse model.
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