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CAS No. | 186139-09-3 | Cat. No. | BCP44501 |
Name | Trodusquemine | ||
Synonyms | MSI-1436; MSI1436; MSI 1436; MSI-1436C; MSI1436C; MSI 1436C; Aminosterol 1436; Aminosterol1436; Aminosterol-1436; | ||
SMILES | CC(C)C(CCC(C)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)NCCCNCCCCNCCCN)C)O)C)OS(=O)(=O)O | ||
Chemical Name | |||
Formula | C37H72N4O5S | M. Wt | 685.07 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Trodusquemine is a protein tyrosine phosphatase PTP-1B inhibitor potentially for the treatment of type 2 diabetes. Trodusquemine significantly enhanced insulin-stimulated tyrosine phosphorylation of insulin receptor (IR) beta and STAT3, direct targets of PTP1B, in HepG2 cells in vitro and/or hypothalamic tissue in vivo. |
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