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CAS No. | 2235394-90-6 | Cat. No. | BCP45170 |
Name | SHP389 | ||
Synonyms | SHP-389; SHP 389; | ||
SMILES | O=C1C2=C(C3=C(Cl)C(NC4CC4)=NC=C3)NN=C2N=C(N(CC5)CCC65[C@H](N)[C@H](C)OC6)N1C | ||
Chemical Name | |||
Formula | C23H29ClN8O2 | M. Wt | 484.98 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SHP389 is an allosteric SHP2 Inhibitor with (SHP2 IC50 - 36 nM). SHP389 modulates MAPK signaling in vivo.SHP389 improved SHP2 biochemical and cellular potency in trend with increasing lipophilicity. |
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