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CAS No. | 1953133-47-5 | Cat. No. | BCP39883 |
Related Products | 2407529-33-1(Giredestrant tartrate) | ||
Name | Giredestrant | ||
Synonyms | GDC-9545; GDC9545; GDC 9545; RG6171; RG-6171; RG 6171; | ||
SMILES | CC1CC2=C(C(N1CC(CO)(F)F)C3=C(C=C(C=C3F)NC4CN(C4)CCCF)F)NC5=CC=CC=C25 | ||
Chemical Name | |||
Formula | C27H31F5N4O | M. Wt | 522.55 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Giredestrant is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. |
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