Amcenestrant New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP38455CAS No. ：2114339-57-8Purity：98%

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Chemical Properties&Biological Activity

CAS No.	2114339-57-8	Cat. No.	BCP38455
Name	Amcenestrant
Synonyms	SAR439859; SAR-439859; SAR 439859;
SMILES	C1CC2=C(C=CC(=C2)C(=O)O)C(=C(C1)C3=C(C=C(C=C3)Cl)Cl)C4=CC=C(C=C4)OC5CCN(C5)CCCF
Chemical Name
Formula	C31H30Cl2FNO3	M. Wt	554.48
Purity	98%	Storage	Store at 4-8°C
Description	Amcenestrant, also known as SAR439859, is an orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SAR439859 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells

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