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CAS No. | 2222844-89-3 | Cat. No. | BCP48205 |
Name | Camizestrant | ||
Synonyms | AZD9833; AZD-9833; AZD 9833;Estrogen receptor antagonist 2; | ||
SMILES | CC1CC2=C(C=CC3=C2C=NN3)C(N1CC(F)(F)F)C4=NC=C(C=C4)NC5CN(C5)CCCF | ||
Chemical Name | |||
Formula | C24H28F4N6 | M. Wt | 476.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Camizestrant is an orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, camizestrant binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells. |
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