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CAS No. | 2009343-14-8 | Cat. No. | BCP47256 |
Name | PHD-1-IN-1 | ||
Synonyms | |||
SMILES | N#CC1=CC=C(C2=CC=CC3=NC=NN23)C=C1 | ||
Chemical Name | |||
Formula | C13H8N4 | M. Wt | 220.23 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe2+ ion and induces the formation of an “Arg367-out” pocket. |
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