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BRD0705 Chemical Structure

BRD0705

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP33275CAS No. ：2056261-41-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 2056261-41-5 Cat. No. BCP33275
Name BRD0705
Synonyms BRD-0705; BRD 0705;
SMILES CCC1(C2=C(NC3=C1C(=O)CC(C3)(C)C)NN=C2)C4=CC=CC=C4
Chemical Name
Formula C20H23N3O M. Wt 321.42
Purity 98% Storage Store at 4-8°C
Description BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC50 of 66 nM and a Kd of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML) research.
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