EN40 New
Data Sheet
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| CAS No. | 2094547-67-6 | Cat. No. | BCP31630 |
| Name | EN40 | ||
| Synonyms | EN 40; EN-40;ALDH3A1 inhibitor EN40; | ||
| SMILES | CC1=C(CN(CC1)C(=O)C=C)C2=CC=CO2 | ||
| Chemical Name | |||
| Formula | C13H15NO2 | M. Wt | 217.27 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | EN40 is a potent and selective, covalent, in vivo-active inhibitor of ALDH3A1 with IC50 of 2 uM, demonstrates no activity against ALDH1A3 and ALDH6A1 at 30 uM; also does not show any observable competition against lysine-reactive probe labeling of A549 proteomes; specifically inhibits the lung cancer cell lines expressing ALDH3A1, but not in the cell lines that do not express ALDH3A1, inhibits ALDH3A1 activity and impairs lung cancer pathogenicity in vivo. | ||
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