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Disulfiram Chemical Structure

Disulfiram

Data Sheet For research use only. Not for human use.
Cat. No. :BCP07331CAS No. :97-77-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 97-77-8 Cat. No. BCP07331
Name Disulfiram
Synonyms Tetraethylthiuram disulfide;TETD;Antabuse;NSC 190940; NSC190940; NSC-190940;
SMILES
Chemical Name
Formula C10H20N2S4 M. Wt 296.54
Purity 98% Storage Store at 4-8°C
Description Disulfiram is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. It blocks the processing of alcohol in the body by inhibiting acetaldehyde dehydrogenase, thus causing an unpleasant reaction when alcohol is consumed. Disulfiram should be used in conjunction with counseling and support. Disulfiram is also being studied as a treatment for cocaine dependence, as it prevents the breakdown of dopamine (a neurotransmitter whose release is stimulated by cocaine); the excess dopamine results in increased anxiety, higher blood pressure, restlessness, and other unpleasant symptoms. Several studies have reported that it has antiprotozoal activity, as well. Disulfiram is the subject of research for use in cancer therapy and as a treatment in HIV cure research (to activate the reservoir of HIV-infected resting CD4 cells) .
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