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Bcl-2-IN-2 Chemical Structure

Bcl-2-IN-2

Data Sheet For research use only. Not for human use.
Cat. No. :BCP36375CAS No. :2383085-86-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2383085-86-5 Cat. No. BCP36375
Name Bcl-2-IN-2
Synonyms
SMILES O=C(NS(=O)(C1=CC=C(NC[C@H]2CC[C@@](O)(C)CC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCC5(CC(N6CCC[C@H]6C7=C(CC)C=CC=C7)C5)CC4)C=C3OC8=CC(C=CN9)=C9N=C8
Chemical Name
Formula C48H57N7O7S M. Wt 876.07
Purity 98% Storage Store at 4-8°C
Description Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL.
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