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CAS No. | 2383085-86-5 | Cat. No. | BCP36375 |
Name | Bcl-2-IN-2 | ||
Synonyms | |||
SMILES | O=C(NS(=O)(C1=CC=C(NC[C@H]2CC[C@@](O)(C)CC2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCC5(CC(N6CCC[C@H]6C7=C(CC)C=CC=C7)C5)CC4)C=C3OC8=CC(C=CN9)=C9N=C8 | ||
Chemical Name | |||
Formula | C48H57N7O7S | M. Wt | 876.07 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL. |
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