SEW2871 New
Data Sheet
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| CAS No. | 256414-75-2 | Cat. No. | BCP35038 |
| Name | SEW2871 | ||
| Synonyms | SEW 2871; SEW-2871; | ||
| SMILES | C1=CC=C(C=C1)C2=C(SC(=C2)C3=NC(=NO3)C4=CC(=CC=C4)C(F)(F)F)C(F)(F)F | ||
| Chemical Name | |||
| Formula | C20H10F6N2OS | M. Wt | 440.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SEW2871 is a S1P1 agonist (sphingosine-1-phosphate type 1 receptor agonist). SEW2871 improves cognitive function in Alzheimer's disease model rats. SEW2871 prolongs heterotopic heart allograft survival in mice. SEW2871 reverse the inhibitory effect of S1P on natural killer cell mediated lysis of K562 tumor cells and dendritic cells but not on cytokine release. SEW2871 prolongs heterotopic heart allograft survival in mice. | ||
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