GW4064 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 278779-30-9 | Cat. No. | BCP22751 |
| Name | GW4064 | ||
| Synonyms | GW4064;GW-4064; | ||
| SMILES | O C(O)C1=CC=CC(/C=C/C2=CC=C(OCC3=C(C(C)C) | ||
| Chemical Name | |||
| Formula | C28H22Cl3NO4 | M. Wt | 542.85 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GW-4064 is a selective agonist of FXR (EC50 = 15 nM). It displays no activity at other nuclear receptors, including the retinoic acid receptor, at concentrations up to 1 μM. GW-4064 upregulates adipokine expression in preadipocytes and HepG2 cells. GW4064 could reduce induction of proinflammatory cytokines by LPS in vitro. | ||
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