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Zidovudine Chemical Structure

Zidovudine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP03622CAS No. :30516-87-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 30516-87-1 Cat. No. BCP03622
Name Zidovudine
Synonyms BW A509U; BWA 509U; BWA-509U; BWA509U;Azidothymidine;AZT;ZDV;Retrovir;
SMILES CC1=CN(C(=O)NC1=O)C2CC(C(O2)CO)N=[N+]=[N-]
Chemical Name
Formula C10H13N5O5 M. Wt 267.24
Purity 98% Storage Store at 4-8°C
Description Zidovudine (Retrovir) is a nucleoside analog reverse transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS. Zidovudine (Retrovir) is an analog of thymidine.Like other reverse transcriptase inhibitors, Zidovudine (Retrovir) works by inhibiting the action of reverse transcriptase, the enzyme that HIV uses to make a DNA copy of its RNA. Reverse transcription is necessary for production of the viral double-stranded DNA, which is subsequently integrated into the genetic material of the infected cell. The triphosphate form also inhibits DNA polymerase used by human cells to undergo cell division, but has approximately 100-fold greater affinity for viral reverse transcriptase.
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