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CAS No. | 314-03-4 | Cat. No. | BCP43719 |
Name | Pimethixene | ||
Synonyms | Pimetixene; BP 400; BP-400; BP400; Calmixene; | ||
SMILES | CN1CCC(=C2C3=CC=CC=C3SC4=CC=CC=C42)CC1 | ||
Chemical Name | |||
Formula | C19H19NS | M. Wt | 293.43 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Pimethixene is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively. |
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