Pimethixene maleate New
Data Sheet
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| CAS No. | 13187-06-9 | Cat. No. | BCP43718 |
| Name | Pimethixene maleate | ||
| Synonyms | Pimetixene maleate; | ||
| SMILES | CN1CCC(=C2C3=CC=CC=C3SC4=CC=CC=C42)CC1.C(=CC(=O)O)C(=O)O | ||
| Chemical Name | |||
| Formula | C23H23NO4S | M. Wt | 409.5 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pimethixene maleate, an antihistamine, anntimigraine agent and antiserotonergic compound, is a highly potent antagonist of a broad range of monoamine receptors, including a variety of serotonin receptors. Pimethixene maleate inhibits 5-HT2A, 5-HT2B, 5-HT2C, 5-HT1A, 5-HT1B, 5-HT6, 5-HT7, Adrenergic α-1A, Dopamine D1 Receptor, Dopamine D2 Receptor, Dopamine D4.4 Receptor, Histamine H1 Receptor, Muscarinic M1 and Muscarinic M2 with pKi of 10.22, 10.44, 8.42, 7.63, < 5, 7.30, 7.28, 7.61, 6.37, 8.19, 7.54, 10.14, 8.61 and 9.38, respectively. | ||
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