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CAS No. | 327033-36-3 | Cat. No. | BCP21212 |
Name | SMI-4a | ||
Synonyms | SMI4a; SMI 4a; TCS-PIM-1-4a; | ||
SMILES | C1=CC(=CC(=C1)C(F)(F)F)C=C2C(=O)NC(=O)S2 | ||
Chemical Name | |||
Formula | C11H6F3NO2S | M. Wt | 273.23 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SMI-4a, also called as TCS-PIM-1-4a, a thiazolidinedione compound, is a potent, selective ATP-competitive inhibitor against Pim protein kinase (IC50 = 24 nM against Pim-1 and 100 nM against Pim-2) with little or no activity against a panel of 58 other kinase. |
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