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CAS No. | 447415-26-1 | Cat. No. | BCP46931 |
Name | NH-3 | ||
Synonyms | NH 3;NH3;Thyromimetic, 5b; | ||
SMILES | CC1=CC(=CC(=C1CC2=CC(=C(C(=C2)C(C)C)O)C#CC3=CC=C(C=C3)[N+](=O)[O-])C)OCC(=O)O | ||
Chemical Name | |||
Formula | C28H27NO6 | M. Wt | 473.52 |
Purity | 98% | Storage | Store at 4-8°C |
Description | NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment. |
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