Reserpine

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP02074CAS No. ：50-55-5Purity：98%

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CAS No.	50-55-5	Cat. No.	BCP02074
Name	Reserpine
Synonyms	Serpalan;
SMILES
Chemical Name
Formula	C33H40N2O9	M. Wt	608.68
Purity	98%	Storage	Store at 4-8°C
Description	Reserpine (Lannett's Serpalan) is an indole alkaloid antipsychotic and antihypertensive drug that has been used for the control of high blood pressure and for the relief of psychotic symptoms, although because of the development of better drugs for these purposes and because of its numerous side-effects, it is rarely used today. The antihypertensive actions of reserpine are a result of its ability to deplete catecholamines (among other monoamine neurotransmitters) from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral vascular resistance. Reserpine irreversibly blocks the vesicular monoamine transporter (VMAT). This normally transports free intracellular norepinephrine, serotonin, and dopamine in the presynaptic nerve terminal into presynaptic vesicles for subsequent release into the synaptic cleft ("exocytosis"). Unprotected neurotransmitters are metabolized by MAO (as well as by COMT) in