Manidipine dihydrochloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 89226-75-5 | Cat. No. | BCP22692 |
| Name | Manidipine dihydrochloride | ||
| Synonyms | CV-4093;CV 4093;CV4093;Manidipine 2HCl;126229-12-7; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C35H40Cl2N4O6 | M. Wt | 683.62 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Manidipine, also known as CV-4093, is a calcium channel blocker (dihydropyridine type) that is used clinically as an antihypertensive. Manidipine is a lipophilic, third-generation dihydropyridine calcium channel antagonist with a high degree of selectivity for the vasculature, thereby inducing marked peripheral vasodilation with negligible cardiodepression. In addition, manidipine does not significantly affect norepinephrine levels, suggesting a lack of sympathetic activation. Manidipine has shown antihypertensive efficacy and appears to be well tolerated in adult and elderly patients with mild or moderate essential hypertension. | ||
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