CP-640186 hydrochloride
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 591778-70-0 | Cat. No. | BCP18564 |
| Related Products | 591778-68-6（CP 640186） | ||
| Name | CP-640186 hydrochloride | ||
| Synonyms | CP 640186 hydrochloride;CP640186 hydrochloride; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C30H36ClN3O3 | M. Wt | 522.08 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: CP-640186, also inhibited both isozymes with IC50s of ~55 nM but was 2–3 times more potent than CP-610431 in inhibiting HepG2 cell fatty acid and TG synthesis. CP-640186 also stimulated fatty acid oxidation in C2C12 cells (ACC2) and in rat epitrochlearis muscle strips with EC50s of 57 nM and 1.3 uM . in vivo: In rats, CP-640186 lowered hepatic, soleus muscle, quadriceps muscle, and cardiac muscle malonyl-CoA with ED50s of 55, 6, 15, and 8 mg/kg. Consequently, CP- 640186 inhibited fatty acid synthesis in rats, CD1 mice, and ob/ob mice with ED50s of 13, 11, and 4 mg/kg, and stimulated rat whole body fatty acid oxidation with an ED50 of ~30 mg/kg. | ||
Recommend Products
More >
-
Clesacostat
Cat. No.：BCP39030
No.：1370448-25-1
Product Details -
Firsocostat (S enantiomer)
Cat. No.：BCP37635
No.：ND-630S
Product Details -
-
-
-
Olumacostat glasaretil
Cat. No.：BCP25136
No.：1261491-89-7
Product Details -
PF05175157
Cat. No.：BCP25103
No.：1301214-47-0
Product Details -
Soraphen A
Cat. No.：BCP25039
No.：122547-72-2
Product Details -
Tags:CP-640186 hydrochloride supplier,CP-640186 hydrochloride purchase,CP-640186 hydrochloride manufacturer,CP-640186 hydrochloride distributor,CP-640186 hydrochloride cost,CP-640186 hydrochloride buy,CP-640186 hydrochloride for sale