BX795
Data Sheet
For research use only. Not for human use.
Get Quotation Now Tel: 0086-17754423994 or orders@biochempartner.com
Real-Time Inquiry ×
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 702675-74-9 | Cat. No. | BCP01899 |
| Name | BX795 | ||
| Synonyms | BX 795;BX-795; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H26IN7O2S | M. Wt | 591.48 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BX-795 effectively blocks PDK1 activity in PC-3 cells, as shown by their ability to block phosphorylation of S6K1, Akt, PKCδ, and GSK3β. BX-795 potently inhibits tumor cell growth on plastic with IC50 of 1.6, 1.4, and 1.9 μM for MDA-468, HCT-116 and MiaPaca cells, respectively. In soft agar, BX-795 displays higher growth inhibition with IC50 of 0.72, and 0.25 μM for MDA-468, and PC-3 cells, respectively. In addition, BX-795, as an inhibitor of the TBK1/IKK?, blocks TBK1- and IKKε-mediated activation of IRF3 and production of IFN-β. In platelet physiological responses, BX795 produces inhibitory effect on 2-MeSADP-induced or collagen-induced aggregation, ATP secretion and thromboxane generation. | ||
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.
Recommend Products
More >
Tags:BX795 supplier,BX795 purchase,BX795 manufacturer,BX795 distributor,BX795 cost,BX795 buy,BX795 for sale