OSU-03012
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CAS No. | 742112-33-0 | Cat. No. | BCP01835 |
Name | OSU-03012 | ||
Synonyms | AR-12;N/AAR-12;OSU03012;OSU 03012; | ||
SMILES | |||
Chemical Name | |||
Formula | C26H19F3N4O | M. Wt | 460.46 |
Purity | 98% | Storage | Store at 4-8°C |
Description | OSU03012; also known as AR12, is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1, a protein in the PI3K/Akt pathway that is involved in the growth and proliferation of cells, including cancer cells. AR-12 may also cause cell death through the induction of stress in the endoplasmic reticulum. We are currently conducting a multi-centered Phase I clinical study of AR-12 in adult patients with advanced or recurrent solid tumors or lymphoma. |
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