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OSU-03012 Chemical Structure

OSU-03012

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01835CAS No. :742112-33-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 742112-33-0 Cat. No. BCP01835
Name OSU-03012
Synonyms AR-12;N/AAR-12;OSU03012;OSU 03012;
SMILES
Chemical Name
Formula C26H19F3N4O M. Wt 460.46
Purity 98% Storage Store at 4-8°C
Description OSU03012; also known as AR12, is an orally available, targeted anti-cancer agent that has been shown in pre-clinical studies to inhibit PDK-1, a protein in the PI3K/Akt pathway that is involved in the growth and proliferation of cells, including cancer cells. AR-12 may also cause cell death through the induction of stress in the endoplasmic reticulum. We are currently conducting a multi-centered Phase I clinical study of AR-12 in adult patients with advanced or recurrent solid tumors or lymphoma.
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