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BAG956 Chemical Structure

BAG956

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01894CAS No. :853910-02-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 853910-02-8 Cat. No. BCP01894
Name BAG956
Synonyms NVP-BAG956;BAG 956;BAG-956;
SMILES
Chemical Name
Formula C28H21N5 M. Wt 427.5
Purity 98% Storage Store at 4-8°C
Description BAG 956 is a dual PDK1 and class I PI 3-kinase inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDK1 and PI3K p110 -α, -β, -δ, and -γ respectively). BAG 956 has been shown to inhibit cellular AKT phosphorylation at Thr308. BAG 956 also blocks cell proliferation and causes arrest in the G1 phase of the cell cycle. BAG 956 has been shown to slow tumor progression in mouse xenograft models.
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