MK-0941 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 752240-01-0 | Cat. No. | BCP42876 |
| Related Products | 1137916-97-2（MK-0941 mesylate） | ||
| Name | MK-0941 | ||
| Synonyms | MK 0941; MK0941; | ||
| SMILES | CCS(=O)(=O)C1=NC=C(C=C1)OC2=CC(=CC(=C2)C(=O)NC3=NN(C=C3)C)OC(C)CO | ||
| Chemical Name | |||
| Formula | C21H24N4O6S | M. Wt | 460.5 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MK-0941 is a glucokinase activator with EC50 values of 0.24 and 0.065 µM at low (2.5 mM) and high (10 mM) concentrations of glucose, respectively. It increases insulin secretion from isolated rat islets of Langerhans and glucose uptake by hepatocytes in vitro. MK-0941 reduces blood glucose levels in high-fat diet-fed db/db mice and in high-fat diet-fed mice with diabetes induced by streptozotocin . | ||
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