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Aurora Kinase Inhibitor III Chemical Structure

Aurora Kinase Inhibitor III

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30248CAS No. :879127-16-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 879127-16-9 Cat. No. BCP30248
Name Aurora Kinase Inhibitor III
Synonyms
SMILES C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=CC(=N3)NC4=CC=CC(=C4)C(F)(F)F
Chemical Name
Formula C21H18F3N5O M. Wt 413.40
Purity 98% Storage Store at 4-8°C
Description Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM). It is selective for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively).
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