SBI-115 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 882366-16-7 | Cat. No. | BCP32736 |
| Name | SBI-115 | ||
| Synonyms | SBI 115; SBI115; | ||
| SMILES | CCS(=O)(=O)C1=NC=C(C(=N1)C(=O)OC2=CC=CC(=C2)C)Cl | ||
| Chemical Name | |||
| Formula | C14H13ClN2O4S | M. Wt | 340.78 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5. TGR5 contributes to hepatic cystogenesis by increasing cAMP and enhancing cholangiocyte proliferation; our data suggest that a TGR5 antagonist alone or concurrently with somatostatin receptor agonists represents a potential therapeutic approach in polycystic liver disease. | ||
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